Abstract

Background

Food insecurity (FI) is a driver of chronic disease. Produce prescription (PRx) interventions pair access to produce with education, but evidence among Medicaid-insured adults remains limited.

Objective

Evaluate the impact of PRx on FI, fruit and vegetable (FV) intake, and psychosocial and clinical outcomes among adults with chronic conditions.

Design

Prospective, non-randomized cohort study with a matched comparison group.

Participants

A total of 125 Medicaid-insured, food-insecure adults with chronic metabolic conditions were enrolled in the intervention cohort and 92 matched to the Supplemental Nutrition Assistance Program (SNAP)-only cohort.

Intervention

Weekly home-delivered produce, registered dietitian-led coaching, and education over 12 months.

Main Measures

FI (USDA 10-item Food Security Survey Module), FV intake (National Cancer Institute screener), depression (PHQ-9), loneliness (UCLA 3-item), fatigue (FACIT-F), healthcare utilization and costs, and blood pressure (BP). For the comparison cohort, some measures were obtained for 6 months of follow-up.

Key Results

At 6 months, based on between-group differences, PRx was associated with greater improvements in FV intake (difference in change: + 0.3 vs. + 0.03 cups/day, p = 0.002) and greater reductions in loneliness (difference in change: −0.6 points, p = 0.022). Between-group differences for FI (−8.2 percentage points, p = 0.26) and moderate-to-severe depression (−10.8 percentage points, p = 0.07) favored PRx but were not statistically significant. At 12 months, no significant between-group differences in healthcare utilization and costs were observed. Among the 105 (84%) intervention participants who completed 12-month follow-up, between the pre- and post-intervention periods, FI declined by 17.1% (p = 0.003), FV intake increased by 0.4 cups/day (p < 0.001), fatigue improved by 3.1 points (p = 0.019), and among participants with elevated baseline BP (n = 73), systolic BP decreased by 8.6 mmHg (p = 0.003).

Discussion

In this study, PRx was associated with improved diet quality and loneliness compared with a SNAP-only comparison. Within-group analyses demonstrated improvements across dietary, psychosocial, and BP outcomes, supporting further evaluation using randomized or comparative designs.

Topic

JGIM

Author Descriptions

Department of Implementation Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Rachel Zimmer DNP, APRN, AGPCNP-C & Sarah Birken PhD

Section of Gerontology and Geriatric Medicine, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA
Rachel Zimmer DNP, APRN, AGPCNP-C & Charlotte Crotts CCRC

Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA
Lindsey Abdelfattah MS & Amresh Hanchate PhD

YMCA of Northwest North Carolina, Winston Salem, NC, 27101, USA
Diane Shenberger MS, RDN, LDN

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