Systematic Reviews
AHRQ (Agency for Healthcare Research and Quality) Evidence Reports
http://www.ahrq.gov/research/findings/evidence-based-reports/index.html
Systematic reviews on a range of clinical topics.
Clinical Evidence
clinicalevidence.bmj.com/x/index.html
A database of systematic reviews grouped by clinical topic, as well as an assortment of EBM resources and training materials.
Cochrane Database of Systematic Reviews
www.cochrane.org/cochrane-reviews
Systematic reviews and literature syntheses on a range of clinical therapeutics
DARE (Database of Abstracts of Reviews of Effects)
http://www.cochrane.org/editorial-and-publishing-policy-resource/database-abstracts-reviews-effects-dare
Critically appraised summaries of systematic reviews of healthcare interventions and of the delivery and organization of health services.
USPSTF (United States Preventive Services Task Force) Systematic Reviews
http://www.uspreventiveservicestaskforce.org/index.html
Systematic reviews of a broad range of clinical preventive health care services (e.g., screenings, counseling, and preventive medications).
Critically Appraised Articles
ACP Journal Club
acpjc.acCponline.org
Structured abstracts of recent high impact articles in general internal medicine or medicine subspecialties, with assessment of methodologic strength, summary of results in clear EBM terms, and expert commentary.
Selected Individual Articles
ACP Journal Wise
http://smartmedicine.acponline.org/
Searchable database of abstracts of published studies found to meet entry validity criteria, with unfiltered user comments. Free to ACP members.
Evidence Updates
http://plus.mcmaster.ca/evidenceupdates/
Free searchable database of abstracts of published studies found to meet entry validity criteria, with unfiltered user comments. Includes links to selected EBM resources.
PubMed Clinical Queries
http://www.ncbi.nlm.nih.gov/pubmed/clinical
Access to all articles in the medical literature via validated search terms aimed at diagnosis, treatment, etiology, prognosis, clinical prediction or systematic reviews.
Clinical Databases
ACP Smart Medicine (American College of Physicians)
http://www.acponline.org/clinical_information/smart_medicine/
An evidence-based clinical decision support tool focused on internal medicine, free to ACP members. All recommendations are rated for evidence quality; provides links to relevant guidelines and primary evidence.
Dynamed
https://dynamed.ebscohost.com/
Fee-based online reference that covers a wide range of clinical topics; provides links to original articles, with mention of level of source evidence for clinical recommendations.
Option Grid
http://www.optiongrid.org/#sthash.aTrhVoks.dpuf
Comparisons of reasonable treatment or screening options for various conditions, oriented to questions frequently asked by patients
MedlinePlus
http://www.nlm.nih.gov/medlineplus/
National Institute of Health’s website designed to instruct patients about various clinical topics. Materials are screened for accuracy and a lack of commercial bias.
Medscape
www.medscape.com/
Fee-based collection of medical information and educational tools designed for providers, featuring news, perspectives, and journal articles.
UpToDate
http://www.uptodate.com/home
Fee-based online or CD reference that covers a wide range of clinical topics in a narrative style; provides links to original articles; substantial reliance on expert opinion.
Clinical Guidelines
CMA (Canadian Medical Association) Clinical Practice Guidelines
https://www.cma.ca/En/Pages/clinical-practice-guidelines.aspx
A clearinghouse of clinical practice guidelines for numerous clinical topics.
National Guideline Clearinghouse
www.guideline.gov
Database of a large number of clinical practice guidelines about a wide variety of clinical topics; the included guidelines are based on varying levels of evidence.
NICE (National Institute for Health and Clinical Excellence)
www.nice.org.uk
UK organization providing guidance on the most effective ways to prevent, diagnose, and treat illness, with goal of reducing inequality and variation.
Trip Database
www.tripdatabase.com
Free online search tool which searches across multiple evidence-based databases, with evidence quality filters
USPSTF Summary Statements
www.uspreventiveservicestaskforce.org/recommendations.htm
Condensed recommendation (extracted from the corresponding systematic review done by USPSTF) regarding preventive health care services.
VA/DoD Clinical Practice Guidelines
http://www.healthquality.va.gov/
Selection of clinical practice recommendations that is a joint effort by U.S. Department of Veterans Affairs and U.S. Department of Defense to improve the health of active-duty and retired military personnel.