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Evidence-Based Medicine Resources

Systematic Reviews

AHRQ (Agency for Healthcare Research and Quality) Evidence Reports
Systematic reviews on a range of clinical topics.

Clinical Evidence
A database of systematic reviews grouped by clinical topic, as well as an assortment of EBM resources and training materials.

Cochrane Database of Systematic Reviews
Systematic reviews and literature syntheses on a range of clinical therapeutics

DARE (Database of Abstracts of Reviews of Effects)
Critically appraised summaries of systematic reviews of healthcare interventions and of the delivery and organization of health services.

USPSTF (United States Preventive Services Task Force) Systematic Reviews
Systematic reviews of a broad range of clinical preventive health care services (e.g., screenings, counseling, and preventive medications).

Critically Appraised Articles

ACP Journal Club
Structured abstracts of recent high impact articles in general internal medicine or medicine subspecialties, with assessment of methodologic strength, summary of results in clear EBM terms, and expert commentary.

Selected Individual Articles

ACP Journal Wise
Searchable database of abstracts of published studies found to meet entry validity criteria, with unfiltered user comments. Free to ACP members.

Evidence Updates
Free searchable database of abstracts of published studies found to meet entry validity criteria, with unfiltered user comments. Includes links to selected EBM resources.

PubMed Clinical Queries
Access to all articles in the medical literature via validated search terms aimed at diagnosis, treatment, etiology, prognosis, clinical prediction or systematic reviews.

Clinical Databases

ACP Smart Medicine (American College of Physicians)
An evidence-based clinical decision support tool focused on internal medicine, free to ACP members. All recommendations are rated for evidence quality; provides links to relevant guidelines and primary evidence.

Fee-based online reference that covers a wide range of clinical topics; provides links to original articles, with mention of level of source evidence for clinical recommendations. 

Option Grid
Comparisons of reasonable treatment or screening options for various conditions, oriented to questions frequently asked by patients

National Institute of Health’s website designed to instruct patients about various clinical topics.  Materials are screened for accuracy and a lack of commercial bias.

Fee-based collection of medical information and educational tools designed for providers, featuring news, perspectives, and journal articles.

Fee-based online or CD reference that covers a wide range of clinical topics in a narrative style; provides links to original articles; substantial reliance on expert opinion.

Clinical Guidelines

CMA (Canadian Medical Association) Clinical Practice Guidelines
A clearinghouse of clinical practice guidelines for numerous clinical topics.

National Guideline Clearinghouse
Database of a large number of clinical practice guidelines about a wide variety of clinical topics; the included guidelines are based on varying levels of evidence.

NICE (National Institute for Health and Clinical Excellence)
UK organization providing guidance on the most effective ways to prevent, diagnose, and treat illness, with goal of reducing inequality and variation.

Trip Database
Free online search tool which searches across multiple evidence-based databases, with evidence quality filters

USPSTF Summary Statements
Condensed recommendation (extracted from the corresponding systematic review done by USPSTF) regarding preventive health care services.

VA/DoD Clinical Practice Guidelines
Selection of clinical practice recommendations that is a joint effort by U.S. Department of Veterans Affairs and U.S. Department of Defense to improve the health of active-duty and retired military personnel.