Diabetes, Lifestyle and Metformin

BOTTOM LINE SUMMARY

Preventing Diabetes: The Impact of Lifestyle Intervention and Metformin

Release Date: September 15, 2016

In patients with prediabetes, both intensive lifestyle interventions and treatment with metformin can prevent or delay the development of type 2 diabetes; however, structured lifestyle interventions targeting 7% weight loss and at least 150 minutes of physical activity a week are most effective. The effects of diabetes prevention efforts are durable, lasting up to 15 years.

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WRITTEN BY THE EVIDENCE BASED MEDICINE TASK FORCE

• Michael E. Bowen MD, MPH, MSCS
• Matthew J. O’Brien MD, MSc
• Namratha R. Kandula, MD, MPH
• Zackary Berger, MD, PhD
• Harry B. Burke, MD, PhD
• Jocelyn A. Carter, MD, MPH
• Jamie Jarmul, BS
• Devan Kansagara, MD, MCR
• Bill Kormos, MD
• Rani Nandiwada, MD
• Heather Sateia, MD
• Jeffrey Tice, MD
• Clark Veet, MD
• James Yeh, MD
• M.E. Beth Smith, DO, MCR

The Bottom Line summaries reflect the expertise and opinions of the SGIM EBM Task Force as of the date of release of this summary.