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Bottom Line Summary

Lorcaserin For Weight Loss

Weight loss at 1 year

The Bottom Line

In obese but relatively healthy patients, lorcaserin with diet and exercise leads to an additional 8 pounds of weight loss over one year but weight is regained when the drug is stopped. The clinical importance of this benefit and the harms of taking lorcaserin for greater than one year are uncertain.

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  1. Reference A : Smith SR, Weissman NJ et al. NEJM 2010. 363:245-56.