Bottom Line Summary
Low Dose Calcium and Vitamin D for Primary Prevention of Fractures in Postmenopasual Women without Osteoporosis
Daily supplementation with ≤ 400 IU of Vitamin D3 and ≤ 1000 mg calcium in community dwelling postmenopausal women is not recommended for primary prevention of fractures. The benefits and harms of larger doses and use in premenopausal women or in men is not known.
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References
- Moyer et al. Vitamin D and calcium supplementation to prevent fractures in adults: US Preventive Services Task Force Recommendation Statement. Ann Intern Med 2013;158:691-696.
- Chung et al. Vitamin D with or without calcium supplementation for prevention of cancer and fractures: an updated meta-analysis for the US Preventive Services Task Force. Ann Intern Med. 2011;155:827-838.
- Jackson et al. Women’s Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med. 2006;354:669-83.